Patient characteristics associated with clustering of RFLP patterns in isolates of Mycobacterium tuberculosis callected from a non-outbreak setting /
(identical to at least one other isolate in the study) or
| Main Author: | |
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| Format: | Thesis eBook |
| Language: | English |
| Published: |
[Place of publication not identified] :
[publisher not identified] ;
1995.
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| Subjects: | |
| Online Access: | Link to OAKTrust copy |
| Summary: | (identical to at least one other isolate in the study) or among all RFLP patterns. Demographic data (age, race, HIV analysis may reveal outbreaks of tuberculosis previously analysis were younger age (less than 50 years of age,) and analyzed for an association with clustering of fingerprint as, the target for RFLP analysis. The resulting fingerprint clustering of patterns (inferring recent transmission) were Computerized analysis was done to calculate similarities epidemiologically related strains exhibiting identical RFLP experiencing the highest rates. fingerprint patterns. Additionally, risk factors for fingerprint patterns. In non-outbreak settings, RFLP from patients at the VA Hospital in Houston, Texas. A total HIV status, with patients not infected with HIV at a higher identified for this study population. Of the 61 clinical isolates fingerprinted, 67% were identical to at least one may allow for distinction of cases due to exogenous nonclustered (not identical to any other isolate). of 61 isolates were collected and fingerprinted using IS6110 of erogenous transmission, as evidenced by clustering of other isolate in the study (therefore clustered). Patient patterns were compared visually and categorized as clustered patterns. The purpose of this study was to identify patients Restriction Fragment Length Polymorphism (RFLP) is a valuable risk factors for clustering identified by logistic regression risk for clustering of patterns. Therefore, erogenous similarity of patterns. Clinical isolates of Mycobacterium status, drug and alcohol usage) collected on all patients was study, with younger patients, and those HIV negative tool for exposing transmission of tuberculosis, with transmission accounts for two-thirds of the cases in this transmission and endogenous reactivation, based upon tuberculosis have been developed to assist in the tuberculosis were collected over an eighteen month period understanding of the epidemiology of the disease. undetected by traditional contact tracing. In addition, RFLP United States, techniques for strain typing of Mycobacterium With the rise in the number of cases of tuberculosis in the within this study population whose tuberculosis is the result |
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| Item Description: | "Major subject: Epidemiology". Vita. |
| Physical Description: | ix, 62 leaves : illustrations ; 28 cm. Also available online. Issued also on microfiche from Lange Micrographics. |
| Bibliography: | Includes bibliographical references. |