Detection of chlorpyrifos-ethyl (Dursban) and its metabolites in urine samples using immunoassays with confirmation by gas chromatography/mass spectrometry /
0.08 ppb. It was also selected because it detects the
| Main Author: | |
|---|---|
| Format: | Thesis eBook |
| Language: | English |
| Published: |
[Place of publication not identified] :
[publisher not identified] ;
1995.
|
| Subjects: | |
| Online Access: | Link to OAKTrust copy |
| Summary: | 0.08 ppb. It was also selected because it detects the 85 ppb. While the metabolite's detection limit is not as attempted to quantify the amount of chlorpyrifos-ethyl in been developed for measuring chlorpyrifos-ethyl been sufficient for the purposes of this study. The cELISA cELISA as a reliable method for detection of chlorpyrifos- Chlorpyrifos-ethyl (Dursban) belongs to the organophosphate chromatography/mass spectrometry (GC/MS), and can be class of pesticides. Many organophosphates, such as commonly determined by measuring cholinesterase inhibition. concentrations in water. Compared to conventional confirmation by GC/MS. The selected cELISA (Millipores desirable as the parent compounds' detection limit, it is EnviroGard chlorpyrifos-ethyl plate kit) is a quantitative ethyl in urine. ethyl in water samples. Even though the parent compound is expensive and time consuming. Immunoassay techniques have for domestic and agricultural purposes because of their form of Enzyme Linked Immunoabsorbent Assay (cELISA), with laboratory test traditionally used to detect chlorpyrifos- metabolized before being excreted in urine, the urinary methodology, these new techniques are economical, rapid, and methods. Therefore, it is not yet possible to recommend this parathion and chlordane, are highly toxic and have restricted primary metabolite 3,5,6-TCP, which was expected in urine, at relatively low toxicity. Exposure to chlorpyrifos-ethyl is samples with the immunoassay. However, traditional GC/MS samples. No correlation was established between the two statistically equivalent to GC/MS results. This study still acceptable. Chlorpyrifos-ethyl was detected in a few techniques failed to detect this pesticide in the same This method requires blood. sample analysis via gas traces of chlorpyrifos-ethyl that are present should have urine samples using the two-step indirect competitive assay usage. Others, including chlorpyrifos-ethyl, are widely used was selected solely because it detects chlorpyrifos-ethyl at |
|---|---|
| Item Description: | "Major subject: Industrial Hygiene". In title, "Dursban" is lacking symbol for trademark. Vita. |
| Physical Description: | xi, 84 leaves : illustrations ; 28 cm. Also available online. Issued also on microfiche from Lange Micrographics. |
| Bibliography: | Includes bibliographical references. |