Hormonal effects on proliferation of adipocyte precursor cells isolated from chicken enbryos /

(GH) , and triiodothyronine (T3) on proliferation of chicken

Bibliographic Details
Main Author: Wu, Ying-Jen, 1966-
Format: Thesis eBook
Language:English
Published: [Place of publication not identified] : [publisher not identified] ; 1994.
Subjects:
Online Access:Link to OAKTrust copy
Description
Summary:(GH) , and triiodothyronine (T3) on proliferation of chicken
(P<.Ol), but stimulation wasnot significantly different
103 ng/mL) and bIN (105ng/mL) stimulated cell growth
a mixture of bovine and porcine glucagon (MGLU, [ ]31.6
adipocyte precursor cells was examined. Adipocyte precursor
adipocyte precursors was proportional to the concentration of
aggregates, and stromal-vascular cells were further separated
cells were isolated from subcutaneous and f emoral adipose
concentrations of bIN did not. Chicken glucagon (cGLU),
containing adipocytes in culture. Confuency from initial
depots from 18-day embryos using collagenase digestion. The
digest was filtered through nylon screens to remove cell
FBS added to medium. Cells did not proliferate in serum-
free media without hormone treatment. High concentrations of
from mature adipocytes by centrifugation. Medium 199
from values achieved with MGLUalone. Addition of T3-
hormones did not increase proliferation above values observed
Influence of glucagon (GLU), insulin (IN), growth hormone
insulin (bIN) (2:10' ng/mL) increased cell sensitivity to T3-
multiplication than any examined hormone treatment (P<.Ol).
multiplied to conf luency and matured into lipid droplet-
ng/mL) and T3 (2:1000 ng/mL) alone significantly (P<.05)
of incubation. Multiplication of fibroblastlike cells and
plating density ( 104 cel 1S/CM2) was achieved by 6 to 7 days
porcine growth hormone (pGH) and bIN alone failed to
stimulate cell multiplication. Several combinations of
stimulated cell proliferation (P<.Ol) although lower
stimulated cell proliferation. High concentrations of bovine
supplemented with antibiotics and fetal bovine serum (FBS)
to stimulate cell proliferation. Combinations of MGLU (2 X
to the effect T3 alone. FBS had a greater impact on cell
treated cells to pGH did not increase responsiveness of cells
was used to support growth of adipocyte precursors. Cells
when a single hormone was used. Porcine GH with bIN failed
Item Description:"Major subject: Poultry Science".
Vita.
Physical Description:ix, 66 leaves : illustrations ; 28 cm.
Also available online.
Bibliography:Includes bibliographical references.