rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Tryptophan biosynthesis by genetically engineered Escherichia coli utilizing different carbon sources
  name:
    name part: Ongay, Reyhan.
    role:
      role term: creator
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: xx
    date issued: 1994
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    form: remote
    extent: xi, 49 leaves : illustrations ; 28 cm.
  abstract: (Pck), and phosphoenolpyruvate synthase (Pps) in a suitable
  abstract: (TktA) activity on aromatics production in Escherichia coli
  abstract: 2-keto-3-deoxy-D-arabinoheptulosonate-7-phosphate (DAHP)
  abstract: acid for animal species and humans, depends largely on
  abstract: additional nitrogen source was studied: glutamine was not
  abstract: biosynthesis. We also compared the efficiency of glucose,
  abstract: Biotransforrnation of chemically synthesized precursors or
  abstract: both of these processes due to expensive precursors in the
  abstract: can be used more efficiently than glucose with overexpression
  abstract: E. coli host cell. While overexpression of AroG alone with
  abstract: former and low yield in the latter hamper the expected large
  abstract: found to improve neither plasmid stability, nor tryptophan
  abstract: glycerol as carbon sources for L-tryptophan biosynthesis.
  abstract: However, very few attempts were made to optimize precursor
  abstract: improve the yield in fermentative processes have focused on
  abstract: in nature as a major component of lignocellulosic biomass,
  abstract: increased to 14% when xylose was used. In the overexpression
  abstract: level obtained from TrpAE overexpression only, overexpression
  abstract: levels in vivo . While investigation along this line was in
  abstract: market of L-tryptophan. Most of the previous studies to
  abstract: medium increased by 28% in xylose compared to glucose.
  abstract: medium. Use of 0.3% xylose+0.7% pyruvic acid and 0.3%
  abstract: microbial processes due to drawback of chemical synthesis:
  abstract: negative effect on L-tryptophan biosynthesis in xylose
  abstract: nitrogen sources are the major microbial production
  abstract: of TktA together with AroG and TrpAE showed a 90% increase
  abstract: of TrpAE only, the specific uwtophan concentration in the
  abstract: of TzpAE only. On the other hand, TktA and AroG can be
  abstract: over the basal level. The overexpression of neither Pps, nor
  abstract: overexpressed together with TrpAE to get higher yields of
  abstract: Overexpression of either AroG or AroG with TktA had a
  abstract: Pck did not improve Ltryptophan biosynthesis either with
  abstract: production by fermentation from inexpensive carbon and
  abstract: progress in our laboratory, positive effects of transketolase
  abstract: synthase (AroG), TktA, phosphoenolpyruvate carboxykinase
  abstract: techniques used. Unfortunately, high production costs of
  abstract: The commercial production of L-uWtophan, an essential ainino
  abstract: the effects of overexpressing the tryptophan operon (TrpAE),
  abstract: The experimental yield obtained from glucose, of 10%
  abstract: the formation of a racemic mixture of DL-tryptophan.
  abstract: TrpAE improved L-tryptophan biosynthesis 28% over the basal
  abstract: TrpAE or AroG and TktA. The effect of glutamine as an
  abstract: tryptophan biosynthesis, in order to optimize production.
  abstract: tryptophan biosynthesis. We conclude that xylose, abundant
  abstract: tryptophan where glucose is favored as a carbon source.
  abstract: varying the specific activity of key enzymes involved in L-
  abstract: was reported by Draths et. al. In this study, we investigate
  abstract: xylose, 0.3% xylose+0.7% pyruvic acid and 0.3% xylose+0.7%
  abstract: xylose+0.7% glycerol as carbon sources did not improve
  note: by Reyhan Ongay.
  note: "Major subject: Chemical Engineering".
  note: Vita.
  note: Also available online.
  note: M.S. Texas A&M University 1994.
  note: Includes bibliographical references.
  subject:
    topic: Major chemical engineering
  identifier: https://hdl.handle.net/1969.1/ETD-TAMU-1994-THESIS-O581
  related item:
    location:
      url: https://hdl.handle.net/1969.1/ETD-TAMU-1994-THESIS-O581
  record info:
    record content source: TXA
    record creation date: 960611
    record change date: 20220103114453.0
    record identifier: in00001304947