Near-infrared spectroscopy for the measurement of glucose in an integrated rotating wall vessel /

68.35 mg/dl for analysis of two sets of spectra from the same

Bibliographic Details
Main Author: Galvan, Mark, 1970-
Format: Thesis eBook
Language:English
Published: [Place of publication not identified] : [publisher not identified] ; 1994.
Subjects:
Online Access:Link to OAKTrust copy
Description
Summary:68.35 mg/dl for analysis of two sets of spectra from the same
biosensors must be developed that are capable of monitoring
cell culture media cannot fulfill these requirements.
Current techniques used to monitor glucose concentration of
day. Thus, near-infrared spectroscopy provides a means for
different day. The serum-based GTSF-2 media, however, seemed
glucose and water solution and a bovine serum-based media
glucose concentration measurement.
In order to maximize cell culture growth in bioreactors,
known as GTSF-2. The results from the glucose and water
line and without any interaction with the cell culture media.
more complex formulation. The analysis of the GTSF-2 spectra
produced a minimum standard deviation of the residuals of
set of data and validation with another set of data from a
solution showed the lowest achievable standard deviation of
that can potentially perform the required measurements on-
the cell culture processes non-invasively and continuously.
the residuals to be 100.5mg/dl with calibration with one
Therefore a near-infrared spectroscopy system is proposed
to provide an enhancement of the glucose signal despite its
Two types of solutions with varying glucose concentrations
were analyzed with the near-infrared spectroscopy system: a
Item Description:"Major subject: Bioengineering".
Vita.
Physical Description:x, 83 leaves : illustrations ; 28 cm.
Also available online.
Bibliography:Includes bibliographical references.