rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Fiber type, meal frequency and colonic cytokinetics
  name:
    name part: Zhang, Jianhu.
    role:
      role term: creator
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: xx
    date issued: 1993
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    form: remote
    extent: x, 87 leaves : illustrations ; 28 cm.
  abstract: The effects of dietary fiber type (cellulose, pectin or oat bran) and meal frequency (gorge or nibble) on colonic short chain fatty acids (SCFAs), in vivo colonic pH and epithelial cell proliferation were examined in male Sprague-Dawley rats. In vivo cell proliferation was measured by [3H]-thymidine incorporation into DNA. Luminal SCFAs were determined by gas chromatography. ber t e. The pectin and oat bran diets produced higher concentrations of all types of SCFAs and of total SCFA than did the cellulose diet at all sites. The higher the concentration of total SCFA in colonic contents, the lower the pH in cecum, proximal and distal colon (r=- O.92, -0.97, -0.88; p=0.01, 0.001, 0.02 respectively). Dry fecal weights were lowest with pectin supplementation and the highest with cellulose. The oat bran diet resulted in an intermediate fecal weight. There were significant negative correlations between pH and crypt height (HC) (r=-O.833, p=0.04); total cells per crypt (TC) (r=-O.817, p=0.05); labeling index (LI) (r=-O.926, p=0.008); and proliferation zone (PZ) (r=-O.981, p=0.0005) in the cecum. There were significant positive correlations between the concentration of total SCFA and HC, TC and PZ (r=0.961, 0.963, 0.845; p=0.01, 0.002, 0.03) in the cecum. No correlation was found between pH or SCFA and cell proliferation in the distal colon, although there were effects of fiber type on H(@, LI and PZ (p=0.03, 0.03, 0.07). The pectin diet produced a higher HC, TC, and PZ in the cecum and LI in the distal colon than did the cellulose diet (p < 0. 05). The oat bran diet resulted in higher HC, TC, LI and PZ than the cellulose diet in the cecum., but lower LI and PZ and higher HC than the pectin diet in the distal colon (p<0.05). Meal frequency. Effect of meal pattern was observed on HC and TC (p=0.0003, 0.0086) in the distal colon. HC and TC were larger in the gorging group than in the nibbling group (p < 0. 05). The results indicate that dietary fiber type affects the concentr…
  note: by Jianhu Zhang.
  note: "Major subject: Nutrition".
  note: Vita.
  note: Also available online.
  note: M.S. Texas A&M University 1993.
  note: Includes bibliographical references.
  subject:
    topic: major nutrition
  identifier: https://hdl.handle.net/1969.1/ETD-TAMU-1993-THESIS-Z63
  related item:
    location:
      url: https://hdl.handle.net/1969.1/ETD-TAMU-1993-THESIS-Z63
  record info:
    record content source: TXA
    record creation date: 960502
    record change date: 20220103134655.0
    record identifier: in00001292025