Effects of vena canal banding in normal dogs and dogs with experimentally-induced multiple portosystematic shunts /
The effects of vena caval banding on hepatic venous pressures and hepatic plasma flow as calculated using hepatic extraction ratio and hepatic clearance were compared between normal dogs (Group 1) and dogs with dimethylnitrosamine experimentally-induced multiple portosystemic shunts (Group 2) both b...
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| Format: | Thesis Book |
| Language: | English |
| Published: |
[Place of publication not identified] :
[publisher not identified] ;
1993.
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| Subjects: | |
| Online Access: | http://proxy.library.tamu.edu/login?url=http://proquest.umi.com/pqdweb?did=745768101&sid=1&Fmt=2&clientId=2945&RQT=309&VName=PQD |
| Summary: | The effects of vena caval banding on hepatic venous pressures and hepatic plasma flow as calculated using hepatic extraction ratio and hepatic clearance were compared between normal dogs (Group 1) and dogs with dimethylnitrosamine experimentally-induced multiple portosystemic shunts (Group 2) both before vena caval banding and for up to 7 days after banding. Comparisons within groups among times were also made. The gradient (caudal vena caval pressure to within + 1-2 mm Hg of portal pressure) between caudal vena caval and portal venous pressures established at banding was maintained after the first hour in both groups. Although caudal vena caval pressures established at banding were unchanged at 7 days in both groups, they were significantly decreased during the first hour in Group 2. Extraction ratios were higher in Group 1 dogs at all times except at 48 hours. Clearance was higher in Group 1 dogs at all times. Hepatic plasma flow did not differ between groups except immediately after banding (flow was greater in Group 2), and there were no differences among times in either group. Vena caval banding in this model of experimentally-induced multiple PSS elevated and maintained caudal vena caval pressure relative to portal venous pressure (after the first hour) for 7 days. However, calculated hepatic plasma flow was not improved by vena caval banding. |
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| Item Description: | Vita. "Major subject: Veterinary Physiology". |
| Physical Description: | xv, 190 leaves : illustrations ; 28 cm. |
| Bibliography: | Includes bibliographical references. |