Toxicity of Radiant Color Powder® in ruminants /

Bibliographic Details
Main Author:	Garland, Tam, 1959-
Other Authors:	Camp, B. J. (degree committee member.), Phillips, T. D. (degree committee member.), Ray, Allen C. (degree committee member.), Reagor, John C. (degree committee member.)
Format:	Thesis Book
Language:	English
Published:	1992.
Subjects:	Dyes and dyeing > Toxicology. Fluorescence. Ruminants > Toxicology. Major toxicology. Academic theses
Online Access:	Link to ProQuest copy Link to OAKTrust copy

Description
Abstract:	The toxicity of Radiant Color Powder®, a commercial fluorescent powder containing 1% 7-diethylamino-4-methyl coumarin and 8.5% 4-methyl benzene sulfonamide, was tested in sheep with single oral dosage levels of 0, 1, 2, 4, and 8 gm/kg body weight. The LD[50] was found to be greater than 8 gm/kg body weight which was comparable to the reported LD[50] values in rats. The compound produced minimal clinical signs and no abnormal clinico-pathologic signs were noted. The 7-diethylamino-4-methyl coumarin and 4-methyl benzene were detected utilizing fluorometric and gas chromatographic techniques, respectively. Both compounds were found in urine and feces, but could not be detected in plasma or serum due to a lack of sensitivity of the methods used.
Item Description:	"Major subject: Toxicology." Typescript (photocopy). Vita.
Physical Description:	xii, 118 leaves : illustrations ; 29 cm
Bibliography:	Includes bibliographical references.