The effect of coenzyme Q10 on physical performance in sedentary asymptomatic individuals /

Bibliographic Details
Main Author: Roberts, Joanne Marie, 1956-
Other Authors: Claborn, Larry (degree committee member.), Gabbard, Carl (degree committee member.), Jessup, George (degree committee member.)
Format: Thesis Book
Language:English
Published: 1989.
Subjects:
Online Access:Link to OAKTrust copy
Description
Abstract:Q10 is a lipid component of the mitochondrial respiratory chain, where its role as electron carrier in the process of oxidative phosphorylation is well acknowledged. Its presence is therefore of fundamental importance in the aerobic adenosine triphosphate (ATP) synthesis mechanism. Several studies have found that supplementation with Q10 improves oxygen consumption (VO2max), cardiac output (CO), stroke volume (SV), maximal workload, and total exercise time in cardiac patients. Even though there has been a plethora of research on the effects of Q10 on performance in cardiac patients, there is a dearth of information on Q10's possible ergogenic effect in asymptomatic individuals. The purpose of this investigation was to determine the effect of supplementation with Q10 utilizing asymptomatic college age males and females on blood Q10 levels, VO2max, CO, and SV. Twenty-four students, twelve males and twelve females with blood Q10 levels (less than or equal to sign) 0.83 ug/ml were studied in a double blind manner for 28 days on the effects of Q10 or placebo supplementation on exercise. Correlations were performed on the initial test data to determine the relationships among the dependent variables. Blood Q10 level that was found to exhibit orthogonality and was analyzed independently using ANOVA. VO2max, CO, and SV were found to exhibit nonorthogonality and were analyzed using multivariate analysis of variance (MANOVA). Any significant MANOVA effects were probed using alpha adjusted (.05/3=0.0167) univariate ANOVA. All other tests were performed with an alpha level of .05..
Item Description:Typescript (photocopy).
Vita.
"Major subject: Physical education."
Physical Description:xii, 118 leaves : illustrations ; 29 cm
Bibliography:Includes bibliographical references.