The relationship of phenylalanine to expression of ochratoxicosis in broiler chickens /

Bibliographic Details
Main Author: Gibson, Robert M., 1951-
Other Authors: Creger, C. R. (degree committee member.), Huff, W. E. (degree committee member.), Kubena, L. F. (degree committee member.)
Format: Thesis Book
Language:English
Published: 1988.
Subjects:
Online Access:ProQuest, Abstract
Link to OAKTrust copy
Description
Abstract:Two studies were conducted to determine the effects of increasing dietary protein or L-phenylalanine on the performance of 3-week old broilers fed diets contaminated with ochratoxin A (OA). In experiment 1, a randomized 3 x 4 factorial design was utilized consisting of 14, 18, 22, and 26% dietary protein and 0, 2, and 4 mg/kg OA. In experiment 2, phenylalanine was evaluated in terms of protecting broiler chickens from the effects of OA. L-phenylalanine was supplemented at 0.0, 0.8, and 2.4% to a 14% protein diet containing either 0.0 or 4 mg/kg OA. There was a significant interaction (p<.05) between protein levels and OA levels. Body weight increased with increasing levels of protein and decreased with increasing levels of OA. Feed to gain ratios were significantly lower (P<.05) in broilers fed 22% and 26% protein and significantly higher (P<.05) in birds fed 4 mg/kg OA. Relative organ weights expressed as a percentage of total body weight were significantly increased (P<.05) as the level of OA was increased. The average mortality was significantly higher (P<.05) in broilers fed 4 mg/kg OA and lowest in birds fed 22% protein. Broilers receiving 4 mg/kg OA had significantly lower packed cell volumes versus birds receiving 0 or 2 mg/kg OA. Dietary protein did not significantly effect total erythocytes, mean corpuscular volumes, hematocrits, packed cell volumes or hemoglobin concentrations. Aspartate aminotransferase, creatine kinase, and serum alkaline phosphatase activities increased significantly as dietary protein increased from 14 to 26%. Broilers receiving 4 mg/kg OA had significantly lower alkaline phosphatase activities versus birds receiving OA at 2 mg/kg. In experiment 2, 42.5% of the birds died during the study when OA was present at 4mg/kg OA in the absence of supplemental L-phenylalanine. However, when L-phenylalanine was supplemented at 0.8 and 2.4%, only 12.5 and 15% of the birds died, respectively...
Item Description:Typescript (photocopy).
Vita.
"Major subject: Nutrition."
Physical Description:x, 123 leaves : illustrations ; 29 cm
Bibliography:Includes bibliographical references (leaves 90-95).