Influence of reactive hyperemia in muscle during exercise /
| Main Author: | |
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| Other Authors: | , , , , |
| Format: | Thesis Book |
| Language: | English |
| Published: |
1988.
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| Subjects: | |
| Online Access: | ProQuest, Abstract Link to OAKTrust copy |
| Abstract: | The purpose of these studies was to determine whether muscle performance during exercise could be enhanced when the exercise was superimposed on reactive hyperemia. In Experiment 1, ten male subjects performed maximal 15-second bicycle ergometer exercise bouts under control conditions and during reactive hyperemia. Total work and peak power were significantly lower during exercise superimposed on reactive hyperemia probably as a result of phosphagen depletion in the muscle. These results, along with the findings reported by others, led to the idea that an animal model may be more suitable for investigating this phenomenon. Thus, in the next experiments, an animal model was developed and utilized to investigate more precisely the effect of reactive hyperemia on exercise performance. Following anesthesia, the abdominal aorta of five Sprague-Dawley rats was occluded with a mechanical occluder to elicit reactive hyperemia. Blood flow velocity in the aorta was measured using a pulsed Doppler flow probe located proximal to the occluder. A 15-min occlusion period yielded a reactive hyperemia of 5 min, during which time the blood flow velocity was significantly greater than either 5 or 10 min periods of occlusion. The right sciatic nerve was stimulated for 5 min (10 V 200 msec 4 Hz.) and tension produced by the gastrocnemius/soleus muscle complex was measured using an isometric force transducer. A comparison of simulated exercise performance under control conditions and during reactive hyperemia indicated that average peak tension, mean tension, and decay from average peak tension were not improved during reactive hyperemia. Mean arterial pressure remained much lower than control exercise during active hyperemia. This problem was resolved in another experiment by occluding only the right iliac artery (n = 7) so that reactive hyperemia occurred only in the exercising limb and by isolating the sciatic nerve to eliminate retrograde conduction of the stimuli which could activate other musculature not involved in the exercise. These procedures resulted in mean arterial pressure that remained at control levels during exercise superimposed on reactive hyperemia. Despite these alterations, average peak tension, mean tension and decay from average peak tension during reactive hyperemia were not significantly different from control exercise values... |
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| Item Description: | Typescript (photocopy). Vita. "Major subject: Physical Education." |
| Physical Description: | x, 142 leaves : illustrations ; 29 cm |
| Bibliography: | Includes bibliographical references. |