Acute equine laminitis : renal morphology and endocrine interplay.
| Main Author: | |
|---|---|
| Other Authors: | , |
| Format: | Thesis Book |
| Language: | English |
| Published: |
1981.
|
| Subjects: | |
| Online Access: | Link to ProQuest Copy Link to OAKTrust copy |
| Abstract: | The levels of testosterone and renin/angiotensin during the acute stages of induced equine laminitis were determined. Renal pathologic conditions were determined for short (4 day) and long (20 days to six weeks) durations of induced laminitis. Testosterone levels during the acute stages of laminitis began to rise 16 hours before clinical signs of lameness occurred and a four fold increase was reached 4-8 hours prior to lameness. The adrenal cortex has been implicated as the source of this androgen and it remains to be determined whether this rise in serum testosterone is causally related to laminitis or is a generalized stress response. Animals that developed laminitis had elevated levels of renin/angiotensin at the time of the first observation of lameness. Twelve hours before clinical signs appeared, renin levels began rising sharply and serum concentration peaked at 17.7 times normal 12 hours after the initial observation of laminitis. Renal involvement is implicated but it remains to be determined whether the rise in renin/angiotensin levels is secondarily related to the disease or is primarily involved in the etiology of the disorder. ... |
|---|---|
| Item Description: | "Major subject: Veterinary Anatomy." Typescript (photocopy). Vita. |
| Physical Description: | x, 107 leaves : illustrations (some color) ; 29 cm |
| Bibliography: | Includes bibliographical references (leaves 103-106). |