rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    non sort: The
    title: toxicity and chemistry of Thamnosma texana
  name:
    name part: Oertli, Ernest Henry
    name part: 1947-
    role:
      role term: creator
  name:
    name part: Bailey, E. Murl
    role:
      role term: degree supervisor.
  name:
    name part: Camp, B. J.
    role:
      role term: degree committee member.
  name:
    name part: Rowe, L. D.
    role:
      role term: degree committee member.
  name:
    name part: Russell, Leon
    role:
      role term: degree committee member.
  name:
    name part: Texas A & M University
    role:
      role term: degree granting institution.
  type of resource: text
  genre: bibliography
  genre: Academic theses
  origin info:
    place:
      place term: xx
    date issued: 1985
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    extent: x, 91 leaves : illustrations ; 29 cm
  abstract: Oral route of exposure of sheep to the air-dried, aerial portions of Thamnosma texana (Dutchman's breeches), resulted in severe photosensitization. Animals fed the plant at 9 or 12 g/kg of body weight/day and held in direct sunlight exhibited signs of phototoxicity within 24-48 hours. The signs manifested were elevated body temperature, photophobia, edema of the muzzle, ears, and vulva, keratoconjunctivitis with edema of the cornea, and exudative dermatitis of the skin of the ears, muzzle, and vulva. Lesser dosages of the plant produced similar effects after several days, except that corneal edema and opacity did not develop. Hepatic lesions were not observed by histopathological studies, a finding consistent with primary photosensitization. The photosensitizing effects of Thamnosma texana can be attributed to the presence of phototoxic linear furocourmarins (psoralens) in the plant. Nine linear furocoumarins and three coumarins were isolated (thin plate chromatography, high pressure liquid chromatography) and identified (mass spectrometry, nuclear magnetic resonance, coinjection) from Thamnosma texana. The identified compounds were xanthotoxin, imperatorin, bergapten, alloimperatorin methyl ether oxide, heraclenin, isopimpinellin, psoralen, oxypeucedanin, byakangelicol, and the coumarins herniarin, osthol, and thamnosmin. These compounds appear to be the agents that account for the observed phototoxicity properties of Thamnosma texana, and consequently for one of its colloquial names, "blisterweed".
  note: "Major subject: Veterinary Toxicology."
  note: Typescript (photocopy).
  note: Vita.
  note: Ph. D. Texas A & M University 1985
  note: Includes bibliographical references (leaves 45-54).
  subject:
    geographic code: n-us-tx
  subject:
    topic: Livestock poisoning plants
    geographic: Texas
  subject:
    topic: Photosensitization, Biological
  subject:
    topic: Rutaceae
  subject:
    topic: Major veterinary toxicology
  subject:
    topic: Livestock poisoning plants
  subject:
    geographic: Texas
  identifier: http://proxy.library.tamu.edu/login
  identifier: https://hdl.handle.net/1969.1/DISSERTATIONS-597622
  related item:
    location:
      url: http://proxy.library.tamu.edu/login
  related item:
    location:
      url: https://hdl.handle.net/1969.1/DISSERTATIONS-597622
  record info:
    record content source: TXA
    record creation date: 870824
    record change date: 20220103135244.0
    record identifier: in00000586073
    language of cataloging:
      language term: eng