rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Genetic studies of metabolic resistance to insecticides in field and laboratory populations of house flies
  name:
    name part: Cluck, Terry Wayne.
    role:
      role term: creator
  name:
    name part: Gold, John R.
    role:
      role term: degree committee member.
  name:
    name part: Johnston, J. S.
    role:
      role term: degree supervisor.
  name:
    name part: Plapp, F. W.
    role:
      role term: degree supervisor.
  name:
    name part: Price, H. James
    role:
      role term: degree committee member.
  name:
    name part: Texas A & M University
    role:
      role term: degree granting institution.
  type of resource: text
  genre: bibliography
  genre: Academic theses
  origin info:
    place:
      place term: xx
    date issued: 1985
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    extent: x, 129 leaves : illustrations ; 29 cm
  abstract: Metabolic resistance (R) controlled by a major gene on chromosome II in house flies is maintained in a heterozygous (R/S) condition in a laboratory strain called R-Propoxur-car. After 120 generations of intermittent selection with insecticide, R-Propoxur-car continued to produce two types of flies: normal wing resistant flies and stubby wing (stw) susceptible flies. Detailed genetic analyses revealed that the strain maintained stw and R in a heterozygous condition (R +/S stw) and that there was no recombination between these loci. The lack of recombination indicated that a crossover suppressor such as an inversion was acting to keep the heterozygous condition fixed. In order to test for crossover suppression in field flies, four natural populations of house flies were sampled and isofemale lines were used to prepare recombination maps of chromosome II. In mapping studies R segregated as a single Mendelian gene, but the map distances both between and within the four colonies were highly variable. The resistant lines showed reduced map distances compared to the susceptible lines indicating that the location of the gene had changed, perhaps through an inversion. When flies from natural populations were crossed with laboratory strains for mapping studies, variability in phenotype resulted. Significantly fewer females produced F1 progeny when outcrossed than when sibmated. Wing mutants, mosaics, homeotic mutants, and unstable eye color mutants occurred at high frequency in the F1, F2, and testcross progeny. These mutations occurred in patterns and frequencies similar to systems, such as hybrid dysgensis in Drosophila melanogaster, in which transposable elements have been induced to move.
  note: "Major subject: Genetics."
  note: Typescript (photocopy).
  note: Vita.
  note: Ph. D. Texas A & M University 1985
  note: Includes bibliographical references (leaves 115-128).
  subject:
    topic: Housefly
    topic: Insecticide resistance
  subject:
    topic: Major genetics
  identifier: http://proxy.library.tamu.edu/login
  identifier: https://hdl.handle.net/1969.1/DISSERTATIONS-439089
  related item:
    location:
      url: http://proxy.library.tamu.edu/login
  related item:
    location:
      url: https://hdl.handle.net/1969.1/DISSERTATIONS-439089
  record info:
    record content source: TXA
    record creation date: 870113
    record change date: 20220103135020.0
    record identifier: in00000415140
    language of cataloging:
      language term: eng