In vitro pathogenesis of equine infectious anemia virus /.

Bibliographic Details
Main Author: Lester, Thomas Lee
Other Authors: Grumbles, L. C. (degree committee member.), Halliwell, H. S. (degree committee member.), Simpson R. B. (degree committee member.)
Format: Thesis Book
Language:English
Published: [College Station, Tex.] : Lester, 1978.
Subjects:
Online Access:Link to ProQuest copy
Link to OAKTrust copy
Description
Abstract:The in vitro pathogenesis of equine infectious anemia (EIA) is described. Light and electron microscopic comparisons of the pathogenesis of both cell adapted (EMS) and Wyoming strain (WS) of EIA virus in equine dermal cell line (CCL-57) and primary horse leukocyte cultures (PHL) were conducted. The EMS virus was cytolytic in both cell systems, while the WS virus was cytolytic in PHL but transformed CCL-57 cells as evidenced by the detection of early proteins in cell membranes. Humoral and cell-mediated immune responses were also investigated but were not involved in the in vitro pathogenesis of EIA virus.
Item Description:"Major subject: Veterinary Microbiology."
Vita.
Physical Description:xi, 100 leaves : illustrations (some color) ; 28 cm
Bibliography:Includes bibliographical references (leaves 82-89).