| Abstract: | D-(-)Trans-1,2-cyclohexanediaminetetraacetic acid (D(-)CDTA) was prepared stereospecifically in good yield by the condensation of the resolved base, D-(-)trans-1,2-cyclohexanediamine, with sodium chloroacetate at 16°C, followed by strong cationic exchange techniques to obtain the free acid. Differences in the IR spectra of the optically active acid and the racemate were noted. D(-)CDTA was used as a spectropolarimetric reagent in the chelometric titration of lead (II). The rate constants for the ligand exchange reaction of D(-)CDTA with PbEDTA were measured polarimetrically. The rate of exchange was more rapid at higher pH values, and changes in the predominant mechanism occurred at pH > 12.7. Several cobalt (III) and nickel (II) bis(triamine) and tris(diamine) complexes were prepared by rapid methods resulting in high purity products by nonaqueous techniques. Optically active metal-ammine complexes were synthesized by similar methods. The absorption spectra of these complexes were obtained. The optical rotatory dispersion and circular dichroism spectra were measured for the optically active complexes and comparisons made with reported values. |
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