http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Some aspects of the chemistry of organo-alkali metal halide clusters using fast atom bombardment ionization and tandem mass spectrometry
Tandem mass spectrometry (TMS) combined with fast-atom bombardment (FAB) ionization has been used for the structural characterization of biomolecules. The advantages of the FAB-TMS experiment have been discussed in previous works, with the major advantages usually relating to mixture analysis. Organo-alkali metal ions of the type [M+xNa-(x-1)H]+ (x = 1-3) are commonly observed in the desorption ionization mass spectra of polar organic molecules. A study of the formation and analytical utility of organo-alkali metal ion formed by fast atom bombardment (FAB) ionization and analyzed by tandem mass spectrometry is presented. It is shown that organo-alkali metal ions of the type [M+xA-(x-1)H]+ (x = 1-3) are formed from [M+A(AX)n]+ complex ions. In addition, structurally significant fragment ions are observed in the [M+A]+ collision induced dissociation (CID) spectra of polar organic molecules not observed in the [M+H]+ CID spectrum. It is further proposed that functional group basicity and organo-alkali metal ion binding energies (D°M--A+) account for specific alkali metal ion binding sites and the dissociation of specific bonds in the molecule. In this work, FAB-TMS is used to study the dissociation reaction of [M+H]+ and [M+A]+ (A = Li, Na, K, Rb, Cs) ions of polar organic molecules. This work shows that additional structural information can be gained by comparing the dissociation reactions of these two different ionic forms.
Includes bibliographical references (leaves 143-149).