Some aspects of the chemistry of organo-alkali metal halide clusters using fast atom bombardment ionization and tandem mass spectrometry /
| Main Author: | |
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| Other Authors: | , , |
| Format: | Thesis Book |
| Language: | English |
| Published: |
1987.
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| Subjects: | |
| Online Access: | ProQuest, Abstract Link to OAKTrust copy |
| Abstract: | Tandem mass spectrometry (TMS) combined with fast-atom bombardment (FAB) ionization has been used for the structural characterization of biomolecules. The advantages of the FAB-TMS experiment have been discussed in previous works, with the major advantages usually relating to mixture analysis. Organo-alkali metal ions of the type [M+xNa-(x-1)H]+ (x = 1-3) are commonly observed in the desorption ionization mass spectra of polar organic molecules. A study of the formation and analytical utility of organo-alkali metal ion formed by fast atom bombardment (FAB) ionization and analyzed by tandem mass spectrometry is presented. It is shown that organo-alkali metal ions of the type [M+xA-(x-1)H]+ (x = 1-3) are formed from [M+A(AX)n]+ complex ions. In addition, structurally significant fragment ions are observed in the [M+A]+ collision induced dissociation (CID) spectra of polar organic molecules not observed in the [M+H]+ CID spectrum. It is further proposed that functional group basicity and organo-alkali metal ion binding energies (D°M--A+) account for specific alkali metal ion binding sites and the dissociation of specific bonds in the molecule. In this work, FAB-TMS is used to study the dissociation reaction of [M+H]+ and [M+A]+ (A = Li, Na, K, Rb, Cs) ions of polar organic molecules. This work shows that additional structural information can be gained by comparing the dissociation reactions of these two different ionic forms. |
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| Item Description: | Typescript (photocopy). Vita. "Major subject: Chemistry." |
| Physical Description: | xv, 150 leaves : illustrations ; 29 cm |
| Bibliography: | Includes bibliographical references (leaves 143-149). |